D-Loop Mutation G42A/G46A Decreases Actin Dynamics

D-Loop Mutation G42A/G46A Decreases Actin Dynamics

Depolymerization and polymerization of the actin filament are indispensable in eukaryotes. The DNase I binding loop (D-loop), which forms part of the interface between the subunits in the actin filament, is an intrinsically disordered loop with a large degree of conformational freedom. Introduction...

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Bibliographic Details
Main Authors: Mizuki Matsuzaki, Ikuko Fujiwara, Sae Kashima, Tomoharu Matsumoto, Toshiro Oda, Masahito Hayashi, Kayo Maeda, Kingo Takiguchi, Yuichiro Maéda, Akihiro Narita
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
depolymerization
polymerization
intrinsically disordered
cofilin
Online Access:https://www.mdpi.com/2218-273X/10/5/736

Internet

https://www.mdpi.com/2218-273X/10/5/736

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