Immune recognition of Gene Transfer Vectors: Focus on Adenovirus as a paradigm

Recombinant Adenovirus (Ad) based vectors have repeatedly demonstrated efficacy, or potential for efficacy in multiple pre-clinical and clinical applications. These applications are numerous, and inclusive of both gene therapy and vaccine based approaches to human or animal diseases. The widesprea...

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Bibliographic Details
Main Authors: Andrea eAmalfitano, Yasser Ali Aldhamen, Sergey S. Seregin
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00040/full