Genetics of Follicular Lymphoma Transformation

Follicular lymphoma (FL) is an indolent disease, but 30%–40% of cases undergo histologic transformation to an aggressive malignancy, typically represented by diffuse large B cell lymphoma (DLBCL). The pathogenesis of this process remains largely unknown. Using whole-exome sequencing and copy-number...

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Bibliographic Details
Main Authors: Laura Pasqualucci, Hossein Khiabanian, Marco Fangazio, Mansi Vasishtha, Monica Messina, Antony B. Holmes, Peter Ouillette, Vladimir Trifonov, Davide Rossi, Fabrizio Tabbò, Maurilio Ponzoni, Amy Chadburn, Vundavalli V. Murty, Govind Bhagat, Gianluca Gaidano, Giorgio Inghirami, Sami N. Malek, Raul Rabadan, Riccardo Dalla-Favera
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713007857