Antiproliferative effect of urolithin A, the ellagic acid-derived colonic metabolite, on hepatocellular carcinoma HepG2.2.15 cells by targeting Lin28a/let-7a axis

An abnormality in the Lin28/let-7a axis is relevant to the progression of hepatitis B virus (HBV)-positive hepatocellular carcinoma (HCC), which could be a novel therapeutic target for this malignant tumor. The present study aimed to investigate the antiproliferative and anti-invasive effects of uro...

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Bibliographic Details
Main Authors: Zhenpeng Qiu, Junxuan Zhou, Cong Zhang, Ye Cheng, Junjie Hu, Guohua Zheng
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
HBx
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000700602&lng=en&tlng=en