Limited Applicability of GW9662 to Elucidate PPARγ-Mediated Fatty Acid Effects in Primary Human T-Helper Cells

Synthetic antagonists of the nuclear receptor PPARγ such as GW9662 are widely used to elucidate receptor-mediated ligand effects. In addition and complementary to recent work, we examined whether GW9662 is suitable to serve for mechanistic investigation in T-helper cells. Human peripheral blood mono...

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Bibliographic Details
Main Authors: Anke Jaudszus, Stefan Lorkowski, Michael Gruen, Alexander Roth, Gerhard Jahreis
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/149628