Identification of hammerhead ribozymes in all domains of life reveals novel structural variations.

Hammerhead ribozymes are small self-cleaving RNAs that promote strand scission by internal phosphoester transfer. Comparative sequence analysis was used to identify numerous additional representatives of this ribozyme class than were previously known, including the first representatives in fungi and...

Full description

Bibliographic Details
Main Authors: Jonathan Perreault, Zasha Weinberg, Adam Roth, Olivia Popescu, Pascal Chartrand, Gerardo Ferbeyre, Ronald R Breaker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21573207/pdf/?tool=EBI