Interleukin-1β and interleukin-1 receptor antagonist appear in grey matter additionally to white matter lesions during experimental multiple sclerosis.

<h4>Background</h4>Multiple sclerosis (MS) has been mainly attributed to white matter (WM) pathology. However, recent evidence indicated the presence of grey matter (GM) lesions. One of the principal mediators of inflammatory processes is interleukin-1β (IL-1β), which is known to play a...

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Bibliographic Details
Main Authors: Marloes Prins, Charlotta Eriksson, Anne Wierinckx, John G J M Bol, Rob Binnekade, Fred J H Tilders, Anne-Marie Van Dam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24376764/?tool=EBI