The Relationship between Pulmonary Damage and Peripheral Vascular Manifestations in Systemic Sclerosis Patients

Systemic sclerosis (SSc) is an autoimmune disease, characterized by the presence of generalized vasculopathy and tissue fibrosis. Collagen vascular disorder in SSc is due to fibroblast and endothelial cell dysfunctions. This leads to collagen overproduction, vascular impairment and immune system abn...

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Bibliographic Details
Main Authors: Barbara Ruaro, Marco Confalonieri, Francesco Salton, Barbara Wade, Elisa Baratella, Pietro Geri, Paola Confalonieri, Metka Kodric, Marco Biolo, Cosimo Bruni
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/5/403