Developmental iodine deficiency resulting in hypothyroidism reduces hippocampal ERK1/2 and CREB in lactational and adolescent rats

<p>Abstract</p> <p>Background</p> <p>Developmental iodine deficiency (ID) leads to inadequate thyroid hormone that impairs learning and memory with an unclear mechanism. Here, we show that hippocampal extracellular signal-regulated kinase (ERK1/2) and cAMP response elem...

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Bibliographic Details
Main Authors: Xi Qi, Hou Yi, Wang Yi, Liu Wanyang, Dong Jing, Chen Jie
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/10/149