Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization.

Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization.

Enterohemorrhagic Escherichia coli O157:H7 (EHEC) is an important food-borne pathogen that colonizes the colon. Transposon-insertion sequencing (TIS) was used to identify genes required for EHEC and E. coli K-12 growth in vitro and for EHEC growth in vivo in the infant rabbit colon. Surprisingly, ma...

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Bibliographic Details
Main Authors: Alyson R Warr, Troy P Hubbard, Diana Munera, Carlos J Blondel, Pia Abel Zur Wiesch, Sören Abel, Xiaoxue Wang, Brigid M Davis, Matthew K Waldor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007652

Internet

https://doi.org/10.1371/journal.ppat.1007652

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