Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis

Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis

Infection by Plasmodium parasites has been a major cause of mortality and morbidity in humans for thousands of years. Despite the considerable reduction of deaths, according to the WHO, over 5 billion people are still at risk, with about 216 million worldwide cases occurring in 2016. More compelling...

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Bibliographic Details
Main Authors: Joshua M. Obiero, Joseph J. Campo, Anja Scholzen, Arlo Randall, Else M. Bijker, Meta Roestenberg, Cornelus C. Hermsen, Andy Teng, Aarti Jain, D. Huw Davies, Robert W. Sauerwein, Philip L. Felgner
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mSphere
Subjects:
CHMI
antibody
malaria
preerythrocytic immunity
protein microarrays
sterile protection
vaccines
Online Access:https://doi.org/10.1128/mSphereDirect.00027-19

Internet

https://doi.org/10.1128/mSphereDirect.00027-19

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