Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Idiopathic Autism Spectrum Disorder and Fragile X Syndrome: A Pilot Study

Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Idiopathic Autism Spectrum Disorder and Fragile X Syndrome: A Pilot Study

Multiple lines of evidence suggest that dysfunction of the metabotropic glutamate receptor subtype 5 (mGluR<sub>5</sub>) plays a role in the pathogenesis of autism spectrum disorder (ASD). Yet animal and human investigations of mGluR<sub>5 </sub>expression provide conflicting...

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Bibliographic Details
Main Authors: James Robert Brašić, Ayon Nandi, David S. Russell, Danna Jennings, Olivier Barret, Samuel D. Martin, Keith Slifer, Thomas Sedlak, John P. Seibyl, Dean F. Wong, Dejan B. Budimirovic
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
binding potential
cortex
caudate nucleus
cingulate
fragile X mental retardation 1 gene <i>(FMR1)</i>
neurodevelopmental disorders
Online Access:https://www.mdpi.com/1422-0067/22/6/2863

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https://www.mdpi.com/1422-0067/22/6/2863

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