Berberine ameliorates diabetic nephropathy by inhibiting TLR4/NF-κB pathway

Berberine ameliorates diabetic nephropathy by inhibiting TLR4/NF-κB pathway

Abstract Background Diabetic nephropathy (DN) is the leading cause of end-stage renal failure, contributing to severe morbidity and mortality in diabetic patients. Berberine (BBR) has been well characterized to exert renoprotective effects in DN progression. However, the action mechanism of BBR in D...

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Bibliographic Details
Main Authors: Liping Zhu, Jiakai Han, Rongrong Yuan, Lei Xue, Wuyan Pang
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Biological Research
Subjects:
Berberine
Streptozotocin
Diabetic nephropathy
Podocytes
TLR4/NF-κB pathway
Inflammatory response
Online Access:http://link.springer.com/article/10.1186/s40659-018-0157-8

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http://link.springer.com/article/10.1186/s40659-018-0157-8

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