REDD1 (regulated in development and DNA damage-1)/autophagy inhibition ameliorates fine particulate matter (PM2.5) -induced inflammation and apoptosis in BEAS-2B cells

REDD1 (regulated in development and DNA damage-1)/autophagy inhibition ameliorates fine particulate matter (PM2.5) -induced inflammation and apoptosis in BEAS-2B cells

This study aimed to investigate the implication of REDD1 on airborne particle matter-induced lung injury and whether it is mediated through autophagy. Cell viability in BEAS-2B cells induced by PM2.5 was measured by CCK-8. RT-qPCR and Western blot were performed to determine mRNA and protein levels...

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Bibliographic Details
Main Authors: Yan Li, Xiaoxiao Xu, Liyan Wang, Xuemei Li, Running Liu, Li Zhang, Yali Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
redd1
pm2.5
lung injury
autophagy
inflammation
Online Access:http://dx.doi.org/10.1080/21655979.2021.1917227

Internet

http://dx.doi.org/10.1080/21655979.2021.1917227

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