Effects of Argentilactone on the Transcriptional Profile, Cell Wall and Oxidative Stress of Paracoccidioides spp.

Paracoccidioides spp., a dimorphic pathogenic fungus, is the etiologic agent of paracoccidioidomycosis (PCM). PCM is an endemic disease that affects at least 10 million people in Latin America, causing severe public health problems. The drugs used against pathogenic fungi have various side effects a...

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Main Authors: Felipe Souto Araújo, Luciene Melo Coelho, Lívia do Carmo Silva, Benedito Rodrigues da Silva Neto, Juliana Alves Parente-Rocha, Alexandre Melo Bailão, Cecília Maria Alves de Oliveira, Gabriel da Rocha Fernandes, Orville Hernández, Juan Guillermo McEwen Ochoa, Célia Maria de Almeida Soares, Maristela Pereira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4703379?pdf=render