Assaying Homodimers of NF-κB in Live Single Cells

NF-κB is a family of heterodimers and homodimers which are generated from subunits encoded by five genes. The predominant classical dimer RelA:p50 is presumed to operate as “NF-κB” in many contexts. However, there are several other dimer species which exist and may even be more functionally relevant...

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Bibliographic Details
Main Authors: Erik W. Martin, Sayantan Chakraborty, Diego M. Presman, Francesco Tomassoni Ardori, Kyu-Seon Oh, Mary Kaileh, Lino Tessarollo, Myong-Hee Sung
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02609/full