Anti-hyperlipidemic effects of Rhizoma Coptidis alkaloids are achieved through modulation of the enterohepatic circulation of bile acids and cross-talk between the gut microbiota and the liver
Molecular and microbiome studies were employed to uncover the mechanisms underlying the cholesterol lowering effects of RC alkaloids. Hyperlipidemic mice were treated with RC alkaloids for 35 days. After treatment, bile acid levels in serum, liver and feces were investigated. Key targets involved in...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-08-01
|
| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464617302220 |