PhyloGibbs: a Gibbs sampling motif finder that incorporates phylogeny.

A central problem in the bioinformatics of gene regulation is to find the binding sites for regulatory proteins. One of the most promising approaches toward identifying these short and fuzzy sequence patterns is the comparative analysis of orthologous intergenic regions of related species. This anal...

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Bibliographic Details
Main Authors: Rahul Siddharthan, Eric D Siggia, Erik van Nimwegen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0010067