Development of [<sup>18</sup>F]LU14 for PET Imaging of Cannabinoid Receptor Type 2 in the Brain

Development of [<sup>18</sup>F]LU14 for PET Imaging of Cannabinoid Receptor Type 2 in the Brain

Cannabinoid receptors type 2 (CB2R) represent an attractive therapeutic target for neurodegenerative diseases and cancer. Aiming at the development of a positron emission tomography (PET) radiotracer to monitor receptor density and/or occupancy during a CB2R-tailored therapy, we herein describe the...

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Bibliographic Details
Main Authors: Rodrigo Teodoro, Daniel Gündel, Winnie Deuther-Conrad, Lea Ueberham, Magali Toussaint, Guy Bormans, Peter Brust, Rareş-Petru Moldovan
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
cannabinoid receptor type 2
naphtyrid-2-one
binding affinity
radiochemistry
fluorine-18 labelling
brain
Online Access:https://www.mdpi.com/1422-0067/22/15/8051

Internet

https://www.mdpi.com/1422-0067/22/15/8051

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