Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma.

Undifferentiated pleomorphic sarcoma/Malignant Fibrous Histiocytoma (MFH) is one of the most common subtypes of human soft tissue sarcoma. Using cross species genomic analysis, we define a geneset from the LSL-Kras(G12D); Trp53(Flox/Flox) mouse model of soft tissue sarcoma that is highly enriched in...

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Bibliographic Details
Main Authors: Jeffrey K Mito, Richard F Riedel, Leslie Dodd, Guy Lahat, Alexander J Lazar, Rebecca D Dodd, Lars Stangenberg, William C Eward, Francis J Hornicek, Sam S Yoon, Brian E Brigman, Tyler Jacks, Dina Lev, Sayan Mukherjee, David G Kirsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2779485?pdf=render