Population structure across scales facilitates coexistence and spatial heterogeneity of antibiotic-resistant infections.

Antibiotic-resistant infections are a growing threat to human health, but basic features of the eco-evolutionary dynamics remain unexplained. Most prominently, there is no clear mechanism for the long-term coexistence of both drug-sensitive and resistant strains at intermediate levels, a ubiquitous...

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Bibliographic Details
Main Authors: Madison S Krieger, Carson E Denison, Thayer L Anderson, Martin A Nowak, Alison L Hill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008010