PASNet: pathway-associated sparse deep neural network for prognosis prediction from high-throughput data

PASNet: pathway-associated sparse deep neural network for prognosis prediction from high-throughput data

Abstract Background Predicting prognosis in patients from large-scale genomic data is a fundamentally challenging problem in genomic medicine. However, the prognosis still remains poor in many diseases. The poor prognosis may be caused by high complexity of biological systems, where multiple biologi...

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Bibliographic Details
Main Authors: Jie Hao, Youngsoon Kim, Tae-Kyung Kim, Mingon Kang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Bioinformatics
Subjects:
Sparse deep neural network
Prognosis prediction
Long-term survival prediction
Pathway-based analysis
Glioblastoma multiforme
TCGA
Online Access:http://link.springer.com/article/10.1186/s12859-018-2500-z

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http://link.springer.com/article/10.1186/s12859-018-2500-z

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