Recovery of aging-related size increase of skin epithelial cells: in vivo mouse and in vitro human study.

The size increase of skin epithelial cells during aging is well-known. Here we demonstrate that treatment of aging cells with cytochalasin B substantially decreases cell size. This decrease was demonstrated on a mouse model and on human skin cells in vitro. Six nude mice were treated by topical appl...

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Bibliographic Details
Main Authors: Igor Sokolov, Natali V Guz, Swaminathan Iyer, Amy Hewitt, Nina A Sokolov, Joseph S Erlichman, Craig D Woodworth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4373822?pdf=render