Daily chemical evodiamine from Chinese prickly ash attenuates osteoclast differentiation through RANKL induced NFAT pathways

Daily chemical evodiamine from Chinese prickly ash attenuates osteoclast differentiation through RANKL induced NFAT pathways

Osteoclasts (OCs) play an important role in a variety of lytic bone diseases. New bone protective therapies exploration has been focused on the suppression of OC formation. In this study, we report that daily chemical evodiamine from Chinese prickly ash, a very common sauce used for stewing meats, a...

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Bibliographic Details
Main Authors: Lei Jiang, Xiaoying Zhao, Jinjin Pei, Lijuan Mei, Yulei Cui, Shuo Wang, Yun Shao, Xiaoling Zhang, Yanduo Tao
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Journal of Functional Foods
Subjects:
Evodiamine
Zanthoxylum bungeanum
RANKL
Osteoclast differentiation
ERK
NFATc1
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617304309

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http://www.sciencedirect.com/science/article/pii/S1756464617304309

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