Risk SNP-induced lncRNA-SLCC1 drives colorectal cancer through activating glycolysis signaling

Abstract Long non-coding RNAs (lncRNAs) play key roles in colorectal carcinogenesis. Here, we aimed to identify the risk SNP-induced lncRNAs and to investigate their roles in colorectal carcinogenesis. First, we identified rs6695584 as the causative SNP in 1q41 locus. The A>G mutation of rs669558...

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Bibliographic Details
Main Authors: Tingting Yan, Chaoqin Shen, Penglei Jiang, Chenyang Yu, Fangfang Guo, Xianglong Tian, Xiaoqiang Zhu, Shiyuan Lu, Bingshe Han, Ming Zhong, Jinxian Chen, Qiang Liu, Yingxuan Chen, Junfang Zhang, Jie Hong, Haoyan Chen, Jing-Yuan Fang
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-020-00446-7