Rictor/TORC2 mediates gut-to-brain signaling in the regulation of phenotypic plasticity in C. elegans.

Animals integrate external cues with information about internal conditions such as metabolic state to execute the appropriate behavioral and developmental decisions. Information about food quality and quantity is assessed by the intestine and transmitted to modulate neuronal functions via mechanisms...

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Bibliographic Details
Main Authors: Michael P O'Donnell, Pin-Hao Chao, Jan E Kammenga, Piali Sengupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5819832?pdf=render