A Population Model of Folate-Mediated One-Carbon Metabolism

Background: Previous mathematical models for hepatic and tissue one-carbon metabolism have been combined and extended to include a blood plasma compartment. We use this model to study how the concentrations of metabolites that can be measured in the plasma are related to their respective intracellul...

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Bibliographic Details
Main Authors: H. Frederik Nijhout, Michael C. Reed, Tanya M. Duncan
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Nutrients
Subjects:
Online Access:http://www.mdpi.com/2072-6643/5/7/2457