Profiling of the perturbed metabolomic state of mouse spleen during acute and chronic toxoplasmosis

Profiling of the perturbed metabolomic state of mouse spleen during acute and chronic toxoplasmosis

Abstract Background Toxoplasma gondii, a common opportunistic protozoan, is a leading cause of illness and mortality among immunosuppressed individuals and during congenital infections. Current therapeutic strategies for toxoplasmosis are not fully effective at curtailing disease progression in thes...

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Bibliographic Details
Main Authors: Xiao-Qing Chen, Chun-Xue Zhou, Hany M. Elsheikha, Shuai He, Gui-Xue Hu, Xing-Quan Zhu
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Parasites & Vectors
Subjects:
Toxoplasma gondii
Spleen
Mass spectrometry
Metabolome
Non-targeted metabolomics
Pathway enrichment analysis
Online Access:http://link.springer.com/article/10.1186/s13071-017-2282-6

Internet

http://link.springer.com/article/10.1186/s13071-017-2282-6

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