Design and development of novel thiazole-sulfonamide derivatives as a protective agent against diabetic cataract in Wistar rats via inhibition of aldose reductase

In recent years, ALR2 (aldose reductase) inhibitors have attracted attention for their effective ability to reduce the progression of diabetes-associated cataracts. Therefore, in the present article, we intended to develop novel thiazole-sulfonamide hybrids as a potent inhibitor of ALR2. These molec...

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Bibliographic Details
Main Authors: Yin Liang, Zhang Mingxue, He Tiangeng
Format: Article
Language:English
Published: De Gruyter 2021-09-01
Series:Heterocyclic Communications
Subjects:
Online Access:https://doi.org/10.1515/hc-2020-0124