Human iPSC-derived neural crest stem cells can produce EPO and induce erythropoiesis in anemic mice

Human iPSC-derived neural crest stem cells can produce EPO and induce erythropoiesis in anemic mice

Inadequate production of erythropoietin (EPO) leads to anemia. Although erythropoiesis-stimulating agents can be used to treat anemia, these approaches are limited by high costs, adverse effects, and the need for frequent injections. Developing methods for the generation and transplantation of EPO-p...

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Bibliographic Details
Main Authors: Valerio Brizi, Sara Buttò, Domenico Cerullo, Angelo Michele Lavecchia, Raquel Rodrigues-Diez, Rubina Novelli, Daniela Corna, Ariela Benigni, Giuseppe Remuzzi, Christodoulos Xinaris
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Stem Cell Research
Subjects:
Pluripotent stem cells
Neural crest cells
Erythropoietin
Anemia
Erythropoiesis
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121003238

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http://www.sciencedirect.com/science/article/pii/S1873506121003238

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