Inflammation and NFκB activation is decreased by hypothermia following global cerebral ischemia

Inflammation and NFκB activation is decreased by hypothermia following global cerebral ischemia

We previously showed that hypothermia attenuates inflammation in focal cerebral ischemia (FCI) by suppressing activating kinases of nuclear factor-kappa B (NFκB). Here we characterize the inflammatory response in global cerebral ischemia (GCI), and the influence of mild hypothermia. Rodents were sub...

Full description

Bibliographic Details
Main Authors: Carla M. Webster, Stephen Kelly, Maya A. Koike, Valerie Y. Chock, Rona G. Giffard, Midori A. Yenari
Format: Article
Language:English
Published: Elsevier 2009-02-01
Series:Neurobiology of Disease
Subjects:
Global cerebral ischemia
Hypothermia
Inflammation
Nuclear factor-kappa B
Microglia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108002672

Similar Items

Similar Items