Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain

Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain

Signaling between the endoplasmic reticulum (ER) and mitochondria regulates a number of key neuronal functions, many of which are perturbed in Alzheimer's disease. Moreover, damage to ER-mitochondria signaling is seen in cell and transgenic models of Alzheimer's disease. However, as yet th...

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Bibliographic Details
Main Authors: Dawn H.W. Lau, Sebastien Paillusson, Naomi Hartopp, Huzefa Rupawala, Gábor M. Mórotz, Patricia Gomez-Suaga, Jenny Greig, Claire Troakes, Wendy Noble, Christopher C.J. Miller
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Neurobiology of Disease
Subjects:
VAPB
PTPIP51
Endoplasmic reticulum
Mitochondria
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120302953

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http://www.sciencedirect.com/science/article/pii/S0969996120302953

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