Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring

Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring

Abstract Background Birth cohort studies link gestational diabetes mellitus (GDM) with impaired cognitive performance in the offspring. However, the mechanisms involved are unknown. We tested the hypothesis that obesity-associated GDM induces chronic neuroinflammation and disturbs the development of...

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Bibliographic Details
Main Authors: Billy Vuong, Gary Odero, Stephanie Rozbacher, Mackenzie Stevenson, Stephanie M. Kereliuk, Troy J. Pereira, Vernon W. Dolinsky, Tiina M. Kauppinen
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Neuroinflammation
Subjects:
Gestational diabetes mellitus
Hippocampus
Microglia
Neurodevelopmental disorder
Neuroinflammation
Recognition memory
Online Access:http://link.springer.com/article/10.1186/s12974-017-0859-9

Internet

http://link.springer.com/article/10.1186/s12974-017-0859-9

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