Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids.

Insects exposed to pesticides undergo strong natural selection and have developed various adaptive mechanisms to survive. Resistance to pyrethroid insecticides in the malaria vector Anopheles gambiae is receiving increasing attention because it threatens the sustainability of malaria vector control...

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Bibliographic Details
Main Authors: Pie Müller, Emma Warr, Bradley J Stevenson, Patricia M Pignatelli, John C Morgan, Andrew Steven, Alexander E Yawson, Sara N Mitchell, Hilary Ranson, Janet Hemingway, Mark J I Paine, Martin J Donnelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2583951?pdf=render