Brainstem Quadruple Aberrant Hyperphosphorylated Tau, Beta-Amyloid, Alpha-Synuclein and TDP-43 Pathology, Stress and Sleep Behavior Disorders

Quadruple aberrant hyperphosphorylated tau (p-τ), amyloid-β peptide, alpha-synuclein and TDP-43 brainstem and supratentorial pathology are documented in forensic ≤40y autopsies in Metropolitan Mexico City (MMC), and p-τ is the major aberrant protein. Post-traumatic stress disorder (PTSD) is associat...

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Main Authors: Lilian Calderón-Garcidueñas, Ravi Philip Rajkumar, Elijah W. Stommel, Randy Kulesza, Yusra Mansour, Adriana Rico-Villanueva, Jorge Orlando Flores-Vázquez, Rafael Brito-Aguilar, Silvia Ramírez-Sánchez, Griselda García-Alonso, Diana A. Chávez-Franco, Samuel C. Luévano-Castro, Edgar García-Rojas, Paula Revueltas-Ficachi, Rodolfo Villarreal-Ríos, Partha S. Mukherjee
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Online Access:https://www.mdpi.com/1660-4601/18/13/6689