Allosteric GABA<sub>A</sub> Receptor Modulators—A Review on the Most Recent Heterocyclic Chemotypes and Their Synthetic Accessibility

Allosteric GABA<sub>A</sub> Receptor Modulators—A Review on the Most Recent Heterocyclic Chemotypes and Their Synthetic Accessibility

GABA<sub>A</sub> receptor modulators are structurally almost as diverse as their target protein. A plethora of heterocyclic scaffolds has been described as modulating this extremely important receptor family. Some made it into clinical trials and, even on the market, some were dismissed....

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Bibliographic Details
Main Authors: Blanca Angelica Vega Alanis, Maria Teresa Iorio, Luca L. Silva, Konstantina Bampali, Margot Ernst, Michael Schnürch, Marko D. Mihovilovic
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
gaba<sub>a</sub> modulators
allosteric modulators
heterocyclic modulators
heterocyclic synthesis
nitrogen heterocycles
Online Access:https://www.mdpi.com/1420-3049/25/4/999

Internet

https://www.mdpi.com/1420-3049/25/4/999

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