Cecal Ligation and Puncture Results in Long-Term Central Nervous System Myeloid Inflammation.

Survivors of sepsis often experience long-term cognitive and functional decline. Previous studies utilizing lipopolysaccharide injection and cecal ligation and puncture in rodent models of sepsis have demonstrated changes in depressive-like behavior and learning and memory after sepsis, as well as e...

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Bibliographic Details
Main Authors: Benjamin H Singer, Michael W Newstead, Xianying Zeng, Christopher L Cooke, Robert C Thompson, Kanakadurga Singer, Ramya Ghantasala, Jack M Parent, Geoffrey G Murphy, Theodore J Iwashyna, Theodore J Standiford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4749127?pdf=render