HLA Associations and Clinical Implications in T-Cell Mediated Drug Hypersensitivity Reactions: An Updated Review

T-cell mediated drug hypersensitivity reactions may range from mild rash to severe fatal reactions. Among them, drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome (DIHS), Stevens-Johnson syndrome/ toxic epidermal necrolysis (SJS/TEN), are some of...

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Bibliographic Details
Main Authors: Chi-Yuan Cheng, Shih-Chi Su, Chi-Hua Chen, Wei-Li Chen, Shin-Tarng Deng, Wen-Hung Chung
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2014/565320