Targeted delivery of lovastatin and tocotrienol to fracture site promotes fracture healing in osteoporosis model: micro-computed tomography and biomechanical evaluation.

Osteoporosis is becoming a major health problem that is associated with increased fracture risk. Previous studies have shown that osteoporosis could delay fracture healing. Although there are potential agents available to promote fracture healing of osteoporotic bone such as statins and tocotrienol,...

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Bibliographic Details
Main Authors: Nurul 'Izzah Ibrahim, Mohd Fadhli Khamis, Mohd Faridz Mod Yunoh, Shahrum Abdullah, Norazlina Mohamed, Ahmad Nazrun Shuid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4272265?pdf=render