Local complement activation is associated with primary graft dysfunction after lung transplantation

Local complement activation is associated with primary graft dysfunction after lung transplantation

BACKGROUND The complement system plays a key role in host defense but is activated by ischemia/reperfusion injury (IRI). Primary graft dysfunction (PGD) is a form of acute lung injury occurring predominantly due to IRI, which worsens survival after lung transplantation (LTx). Local complement activa...

Full description

Bibliographic Details
Main Authors: Hrishikesh S. Kulkarni, Kristy Ramphal, Lina Ma, Melanie Brown, Michelle Oyster, Kaitlyn N. Speckhart, Tsuyoshi Takahashi, Derek E. Byers, Mary K. Porteous, Laurel Kalman, Ramsey R. Hachem, Melanie Rushefski, Ja’Nia McPhatter, Marlene Cano, Daniel Kreisel, Masina Scavuzzo, Brigitte Mittler, Edward Cantu III, Katrine Pilely, Peter Garred, Jason D. Christie, John P. Atkinson, Andrew E. Gelman, Joshua M. Diamond
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-09-01
Series:JCI Insight
Subjects:
Pulmonology
Online Access:https://doi.org/10.1172/jci.insight.138358

Internet

https://doi.org/10.1172/jci.insight.138358

Similar Items