Interleukin-17 aggravates right ventricular remodeling via activating STAT3 under both normoxia and hypoxia

Abstract Objective Proinflammatory cytokine interleukin 17 (IL-17) is involved in ventricular remodeling, mainly of the left ventricle. This study was designed to explore the role of IL-17 played in the pathogenesis of right ventricular hypertrophy (RVH), aiming to provide a novel treatment target o...

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Bibliographic Details
Main Authors: Jing Huang, Wei Zhang, Cai-lian Zhang, Lei Wang
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-021-02069-4