Quantification of BNN27, a novel neuroprotective 17‐spiroepoxy dehydroepiandrosterone derivative in the blood and retina of rodents, after single intraperitoneal administration

Quantification of BNN27, a novel neuroprotective 17‐spiroepoxy dehydroepiandrosterone derivative in the blood and retina of rodents, after single intraperitoneal administration

Abstract BNN27 is a novel 17‐spiroepoxy derivative of the neurosteroid Dehydroepiandrosterone with neuroprotective properties. The purpose of this study was the detection and quantification of BNN27 after single intraperitoneal administration, in the serum and retina of normal rodents. Forty‐two C57...

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Bibliographic Details
Main Authors: Chrysanthi Tsika, Manolis N. Tzatzarakis, Sophia G. Antimisiaris, Pavlina Tsoka, Paschalis Efstathopoulos, Ioannis Charalampopoulos, Achille Gravanis, Miltiadis K. Tsilimbaris
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Pharmacology Research & Perspectives
Subjects:
blood–retinal barrier
BNN27
LC‐MS
neuroprotection
pharmacokinetics
steroids
Online Access:https://doi.org/10.1002/prp2.724

Internet

https://doi.org/10.1002/prp2.724

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