Poly(HydroxyButyrate-co-HydroxyValerate) (PHBHV) Nanocarriers for Silymarin Release as Adjuvant Therapy in Colo-rectal Cancer

Poly(HydroxyButyrate-co-HydroxyValerate) (PHBHV) Nanocarriers for Silymarin Release as Adjuvant Therapy in Colo-rectal Cancer

The aim of this study was to address one of the major challenges of the actual era of nanomedicine namely, the bioavailability of poorly water soluble drugs such as Silymarin. We developed new, biodegradable, and biocompatible nanosized shuttles for Silymarin targeted delivery in colon-cancer cells....

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Bibliographic Details
Main Authors: Ionut-Cristian Radu, Ariana Hudita, Catalin Zaharia, Paul O. Stanescu, Eugenia Vasile, Horia Iovu, Miriana Stan, Octav Ginghina, Bianca Galateanu, Marieta Costache, Peter Langguth, Aristidis Tsatsakis, Kelly Velonia, Carolina Negrei
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Pharmacology
Subjects:
nanocarriers
drug delivery
colo-rectal cancer
Silymarin
Poly(HydroxyButyrate-co-HydroxyValerate) (PHBHV)
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00508/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00508/full

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