CD161+ MAIT cells are severely reduced in peripheral blood and lymph nodes of HIV-infected individuals independently of disease progression.

CD161+ MAIT cells are severely reduced in peripheral blood and lymph nodes of HIV-infected individuals independently of disease progression.

Mucosal-associated invariant T (MAIT) cells are characterized by the combined expression of the semi-invariant T cell receptor (TCR) Vα7.2, the lectin receptor CD161, as well as IL-18R, and play an important role in antibacterial host defense of the gut. The current study characterized CD161(+) MAIT...

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Bibliographic Details
Main Authors: Johanna Maria Eberhard, Philip Hartjen, Silke Kummer, Reinhold E Schmidt, Maximilian Bockhorn, Clara Lehmann, Ashwin Balagopal, Joachim Hauber, Jan van Lunzen, Julian Schulze zur Wiesch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4219715?pdf=render

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http://europepmc.org/articles/PMC4219715?pdf=render

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