TNF-alpha regulates the effects of irradiation in the mouse bone marrow microenvironment.

TNF-alpha regulates the effects of irradiation in the mouse bone marrow microenvironment.

BACKGROUND: Secondary bone marrow (BM) myelodysplastic syndromes (MDS) are increasingly common, as a result of radio or chemotherapy administered to a majority of cancer patients. Patients with secondary MDS have increased BM cell apoptosis, which results in BM dysfunction (cytopenias), and an incre...

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Bibliographic Details
Main Authors: Ana Sofia Cachaço, Tânia Carvalho, Ana Cristina Santos, Cátia Igreja, Rita Fragoso, Catarina Osório, Manuela Ferreira, Jacinta Serpa, Sofia Correia, Perpétua Pinto-do-O, Sérgio Dias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2813873?pdf=render

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http://europepmc.org/articles/PMC2813873?pdf=render

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