Transcriptome-Wide Analysis of Interplay between mRNA Stability, Translation and Small RNAs in Response to Neuronal Membrane Depolarization

Transcriptome-Wide Analysis of Interplay between mRNA Stability, Translation and Small RNAs in Response to Neuronal Membrane Depolarization

Experience-dependent changes to neural circuitry are shaped by spatially-restricted activity-dependent mRNA translation. Although the complexity of mRNA translation in neuronal cells is widely appreciated, translational profiles associated with neuronal excitation remain largely uncharacterized, and...

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Bibliographic Details
Main Authors: Dylan J. Kiltschewskij, Murray J. Cairns
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
translation
post-transcriptional regulation
neuron
ribosome profiling
RNA degradation
microRNA
Online Access:https://www.mdpi.com/1422-0067/21/19/7086

Internet

https://www.mdpi.com/1422-0067/21/19/7086

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