Symmetric Projection Attractor Reconstruction analysis of murine electrocardiograms: Retrospective prediction of Scn5a+/- genetic mutation attributable to Brugada syndrome

Background: Life-threatening arrhythmias resulting from genetic mutations are often missed in current electrocardiogram (ECG) analysis. We combined a new method for ECG analysis that uses all the waveform data with machine learning to improve detection of such mutations from short ECG signals in a m...

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Bibliographic Details
Main Authors: Esther Bonet-Luz, MMath, PhD, Jane V. Lyle, BSc, Christopher L.-H. Huang, MA, BMBCh, DM, DSc, PhD, MD, ScD, Yanmin Zhang, MD, PhD, Manasi Nandi, BSc, PhD, Kamalan Jeevaratnam, DAHP, DVM, MMedSC, PhD, MRCVS, Philip J. Aston, BSc, PhD
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Heart Rhythm O2
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666501820301161