Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species

Ageing-associated DNA methylation dynamics are a molecular readout of lifespan variation among mammalian species

Abstract Background Mammalian species exhibit a wide range of lifespans. To date, a robust and dynamic molecular readout of these lifespan differences has not yet been identified. Recent studies have established the existence of ageing-associated differentially methylated positions (aDMPs) in human...

Full description

Bibliographic Details
Main Authors: Robert Lowe, Carl Barton, Christopher A. Jenkins, Christina Ernst, Oliver Forman, Denise S. Fernandez-Twinn, Christoph Bock, Stephen J. Rossiter, Chris G. Faulkes, Susan E. Ozanne, Lutz Walter, Duncan T. Odom, Cathryn Mellersh, Vardhman K. Rakyan
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Genome Biology
Subjects:
Ageing
Methylation
Epigenetics
Online Access:http://link.springer.com/article/10.1186/s13059-018-1397-1

Internet

http://link.springer.com/article/10.1186/s13059-018-1397-1

Similar Items