Putting into practice domain-linear motif interaction predictions for exploration of protein networks.

PDZ domains recognise short sequence motifs at the extreme C-termini of proteins. A model based on microarray data has been recently published for predicting the binding preferences of PDZ domains to five residue long C-terminal sequences. Here we investigated the potential of this predictor for dis...

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Bibliographic Details
Main Authors: Katja Luck, Sadek Fournane, Bruno Kieffer, Murielle Masson, Yves Nominé, Gilles Travé
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206016?pdf=render