Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies

Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies

Abstract Background A cationic liposome-PEG-PEI complex (LPPC) was employed as a carrier for achieving targeted delivery of drug to human epidermal growth factor receptor-2 (HER2/neu)-expressing breast cancer cells. LPPC can be easily loaded with an anti-tumor drug and non-covalently associated with...

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Bibliographic Details
Main Authors: Yu-Ling Lin, Nu-Man Tsai, Chia-Hung Chen, Yen-Ku Liu, Chung-Jen Lee, Yi-Lin Chan, Yu-Shan Wang, Yuan-Ching Chang, Chi-Hsin Lin, Tse-Hung Huang, Chao Ching Wang, Kwan-Hwa Chi, Kuang-Wen Liao
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Nanobiotechnology
Subjects:
Lipo-PEG-PEI complex
Curcumin
Doxorubicin
Herceptin
Drug delivery
Online Access:http://link.springer.com/article/10.1186/s12951-019-0457-3

Internet

http://link.springer.com/article/10.1186/s12951-019-0457-3

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